Ion-exchange Chromatography Resins

“In Ion-exchange Chromatography (IEX), proteins are separated based on differences in their surface charge. Purification relies on a reversible interaction between a charged protein and a support or ligand with an opposite charge (ionic interactions). In gel filtration chromatography, purified proteins become diluted, whereas in this method, they do not. The support (stationary phase) in this technique contains numerous acidic and basic functional groups. These basic ion exchangers consist of positively charged groups and are termed anion exchangers. Cationic exchangers carry negatively charged groups that attract positively charged molecules. The Ion-exchange Chromatography resins produced by Noavarane Zist Gostar Org Co. are based on the natural polymer agarose and have an average particle size ranging from 40 to 160 micrometers (μm).

Considering customer requirements for purifying various therapeutic proteins to very high purity, there are instances where Ion-exchange Chromatography resins with smaller particle sizes are necessary. Thanks to the company’s advanced particle sizing system, it is possible to supply this type of Ion-exchange Chromatography resin promptly.

“Ion Interaction between Charged protein with opposite charged Ligand”

ArgPure DEAE Agarose Fast Flow

ArgPure Q Agarose Fast Flow

ArgPure CM Agarose Fast Flow

ArgPure SP Agarose Fast Flow

ArgPure S Agarose Fast Flow

“High Performance Ion Exchange”

ArgPure Capto DEAE Agarose

ArgPure Capto Q Agarose

ArgPure Capto CM Agarose

ArgPure Capto SP Agarose